Here is why vaccinated people still need to wear mask

News Network
December 9, 2020

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Dec 9: The new Covid-19 vaccines from Pfizer and Moderna seem to be remarkably good at preventing serious illness. But it’s unclear how well they will curb the spread of the coronavirus.

That’s because the Pfizer and Moderna trials tracked only how many vaccinated people became sick with Covid-19. That leaves open the possibility that some vaccinated people get infected without developing symptoms and could then silently transmit the virus — especially if they come in close contact with others or stop wearing masks.

If vaccinated people are silent spreaders of the virus, they may keep it circulating in their communities, putting unvaccinated people at risk.

“A lot of people are thinking that once they get vaccinated, they’re not going to have to wear masks anymore,” said Michal Tal, an immunologist at Stanford University. “It’s really going to be critical for them to know if they have to keep wearing masks because they could still be contagious.”

In most respiratory infections, including the new coronavirus, the nose is the main port of entry. The virus rapidly multiplies there, jolting the immune system to produce a type of antibodies that are specific to the mucosa, the moist tissue lining the nose, mouth, lungs and stomach. If the same person is exposed to the virus a second time, those antibodies, as well as immune cells that remember the virus, rapidly shut down the virus in the nose before it gets a chance to take hold elsewhere in the body.

The coronavirus vaccines, in contrast, are injected deep into the muscles and quickly absorbed into the blood, where they stimulate the immune system to produce antibodies. This appears to be enough protection to keep the vaccinated person from getting ill.

Some of those antibodies will circulate to the nasal mucosa and stand guard there, but it’s not clear how much of the antibody pool can be mobilized or how quickly. If the answer is not much, then viruses could bloom in the nose — and be sneezed or breathed out to infect others.

“It’s a race: It depends whether the virus can replicate faster, or the immune system can control it faster,” said Marion Pepper, an immunologist at the University of Washington in Seattle. “It’s a really important question.”

This is why mucosal vaccines, like nasal spray FluMist or the oral polio vaccine, are better than intramuscular injections at fending off respiratory viruses, experts said.

The next generation of coronavirus vaccines may elicit immunity in the nose and the rest of the respiratory tract, where it’s most needed. Or people could get an intramuscular injection followed by a mucosal boost that produces protective antibodies in the nose and throat.

The coronavirus vaccines have proved to be powerful shields against severe illness, but that is no guarantee of their efficacy in the nose. The lungs — the site of severe symptoms — are much more accessible to the circulating antibodies than the nose or throat, making them easier to safeguard.

“Preventing severe disease is easiest, preventing mild disease is harder, and preventing all infections is the hardest,” said Deepta Bhattacharya, an immunologist at the University of Arizona. “If it’s 95% effective at preventing symptomatic disease, it’s going to be something less than that in preventing all infections, for sure.”

Still, he and other experts said they were optimistic that the vaccines would suppress the virus enough even in the nose and throat to prevent immunized people from spreading it to others.

“My feeling is that once you develop some form of immunity with the vaccine, your ability to get infected will also go down,” said Akiko Iwasaki, an immunologist at Yale University. “Even if you’re infected, the level of virus that you replicate in your nose should be reduced.”

The vaccine trials have not produced data on how many vaccinated people were infected with the virus but did not have symptoms. Some hints are emerging, however.

AstraZeneca, which announced some of its trial results in November, said that volunteers had been testing themselves regularly for the virus and that those results suggested that the vaccine might prevent some infections.

Pfizer will test a subset of its trial participants for antibodies against a viral protein called N. Because the vaccines have nothing to do with this protein, N antibodies would reveal whether the volunteers had become infected with the virus after immunization, said Jerica Pitts, a spokeswoman for the company.

Moderna also plans to analyze blood from all its participants and test for N antibodies.

“It will take several weeks before we can expect to see those results,” said Colleen Hussey, a spokeswoman for Moderna.

The trials have so far analyzed only blood, but testing for antibodies in mucosa would confirm that the antibodies can travel to the nose and mouth. Tal’s team is planning to analyze matched blood and saliva samples from volunteers in the Johnson & Johnson trial to see how the two antibody levels compare.

In the meantime, Bhattacharya said, he was encouraged by recent work showing that people who received an intramuscular flu vaccine had abundant antibodies in the nose. And a study of Covid-19 patients found that antibody levels in saliva and blood were closely matched — suggesting that a strong immune response in the blood would also protect mucosal tissues.

Only people who have virus teeming in their nose and throat would be expected to transmit the virus, and the lack of symptoms in the immunized people who became infected suggests that the vaccine may have kept the virus levels in check.

But some studies have suggested that even people with no symptoms can have high amounts of coronavirus in their nose, noted Dr. Yvonne Maldonado, who represents the American Academy of Pediatrics at meetings of the Federal Advisory Committee on Immunization Practices. The first person confirmed to be reinfected with the coronavirus, a 33-year-old man in Hong Kong, also did not have symptoms but harboured enough virus to infect others.

Vaccinated people who have a high viral load but don’t have symptoms “would actually be, in some ways, even worse spreaders because they may be under a false sense of security,” Maldonado said.

Tal said she was concerned by monkey studies showing that some vaccinated animals did not get ill but still had virus in their nose.

But those monkeys were intentionally exposed to massive amounts of virus and still had less virus than unvaccinated animals, said John Moore, a virus expert at Weill Cornell Medicine in New York.

“The more you reduce viral load, the less likely you are to be transmissible,” Moore said. But “all of these are things where data trumps theory, and we need the data.”

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Agencies
March 26,2025

The airstrikes led by the United States have killed at least 25 civilians in Yemen over the past week, marking the deadliest week of bombing on the country since the final months of the Washington-backed Saudi war in January 2022.

In a report released on Tuesday, the Yemen Data Project said the 25 civilians were the victims of 38 US-led aerial assaults on March 15-21, adding that 28 people were also injured in the attacks.

The independent tracker also said that 21 out of the 38 US air raids hit non-military, civilian targets.

“Civilian targets hit included: a medical storage facility, a medical center, a school, a wedding hall, residential areas, a cotton gin facility, a health office, Bedouin tents, and Al-Eiman University,” it said.

The deadliest US strike in the first week of US bombing campaign struck a residential area in Yemen’s northwestern Sa'ada province, killing 10 civilians and wounding 11 others, among them children.

The US began bombing Yemen on March 15, a few days after Yemen resumed its operation against Israeli-linked ships in response to Israel’s Gaza aid blockade that violated a ceasefire with the Hamas resistance group.

The Yemeni Armed Forces began their anti-Israel naval campaign in November 2023, a month after the occupying regime waged a genocidal war on the Gaza Strip.

The Yemeni forces halted their attacks in solidarity with the Palestinians in January, when Israel accepted a three-phase Gaza ceasefire.

Two months later, however, Israel unilaterally broke the Gaza truce and resumed its brutal onslaught on the besieged territory.

On Tuesday, Yemeni media reported 17 US strikes on Sa'ada and two more on the nearby 'Amran province.

The reports said American warplanes carried out "aggressive air raids... causing material damage to citizens' property," but gave no details of casualties.

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News Network
April 4,2025

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Israel has announced the launch of a new ground onslaught in Gaza City, with rescuers saying military aggression has killed at least 30 people across the Palestinian territory since dawn.

In Gaza City, the Israeli military said ground troops had begun pushing into the Shejaiya neighborhood to expand the so-called "security zone" there, claiming that civilians had been allowed to evacuate the area. 

Initial reports, however, said a Palestinian woman and her daughter were just killed in an Israeli artillery shelling on displaced people in Shejaiya.

Gaza's civil defense agency said Israeli military aggression had killed at least 30 people in the Palestinian territory since dawn, adding that the toll was "not final".

A single Israeli strike on Khan Yunis killed at least 25 people, a medical source at the southern city's Nasser Hospital said. 

"The situation is very dangerous, and there is death coming at us from every direction," Elena Halas told AFP reportedly via text message, adding that she and her family were trapped in her sister's house in Shejaiya.

Israel has pushed since the collapse of a short-lived truce in the war to seize territory in Gaza. Simultaneously, it has escalated attacks on Lebanon and Syria, with a strike in the south Lebanese city of Sidon killing a Hamas commander along with his son on Friday. 

Minister of military affairs Israel Katz had said on Wednesday that Israel would bolster its military presence inside the Gaza Strip to "seize large areas that will be incorporated into Israeli security zones", without specifying how much territory.

Prime minister Benjamin Netanyahu said the military was dividing Gaza and "seizing territory" to force Hamas to free the remaining captives seized in the October 2023 operation inside southern settlements. 

Netanyahu has said his regime is working closely with the US to implement President Donald Trump's plan to displace Gazans.

Latest air raids have targeted Gaza City, as well as Beit Lahia, Rafah, and Khan Yunis, killing dozens of people and injuring several others.

On Thursday, hundreds of thousands of fleeing Gazans sought shelter in one of the biggest mass displacements of the war, as Israeli forces advanced into the ruins of the city of Rafah. 

A day after declaring their intention to capture large swathes of the crowded territory, Israeli forces pushed into the city on Gaza's southern edge which had served as a last refuge for people fleeing other areas for much of the war.

The Ministry of Health in Gaza said on Thursday that 112 Palestinians were killed by Israeli airstrikes, with at least 70 of those deaths taking place in Gaza City, in the north of the strip. 

Gaza's civil defense agency said women and children were among the dead, while six people were still unaccounted for in the strike on Dar al-Arqam School in the al-Tuffah neighborhood, northeast of Gaza City, including a pregnant woman who was expecting twins. 

Beit Hanoun Mayor Mohammad Nazek Al-Kafarna was one of the victims of the Israeli strike that hit the school on Thursday.

The Health Ministry said on Thursday that 1,163 people have been killed in the Palestinian territory since Israel resumed intense bombing on March 18, bringing the overall death toll since the war began to 50,523.

The usurping entity accepted longstanding negotiation terms by the Hamas resistance group under a Gaza ceasefire, which began on January 19.

On March 18, however, Israel unilaterally broke the truce and resumed its relentless bombing of Gaza.

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News Network
March 28,2025

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When the ground violently shook beneath his feet, Prem Kishore Mohanty, an Indian expatriate in Bangkok, was attending his five-year-old daughter's school sports day. What began as a routine event—children competing, parents cheering—quickly turned into a moment of panic as tremors struck.

"I felt my head spinning and had to sit down. The overhead lights swayed, and chairs moved," said Mr. Mohanty, 44. The school's PA system quickly announced an emergency evacuation, directing everyone to the outdoor field while warning against using nearby lanes lined with high-rise towers.

Water from rooftop swimming pools, including those at the InterContinental Bangkok, cascaded down buildings, as captured in viral videos.

Fear and Chaos as Bangkok Shakes
The 7.7-magnitude earthquake, with its epicenter in Myanmar, sent powerful tremors into Thailand, bringing Bangkok to an abrupt standstill. Public transport was suspended, traffic snarled, and people evacuated buildings, waiting anxiously for the all-clear.

Earthquakes are rare in Bangkok, a city more accustomed to heat and monsoons than seismic shocks. For the Mohanty family, who live in a high-rise apartment in Sukhumvit, confusion and fear gripped them as the evacuation began.

"It was terrifying. We were told to take the fire escape stairwell and wait outside. There was no time to think," Mr. Mohanty recalled.

Now safe, he remains shaken by the unexpected jolt that turned a normal day into a moment of chaos for his family and thousands across the city.

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