Omicron gives better immune responses than booster shot, reveal Studies

News Network
May 16, 2022

People who are vaccinated and then get infected with Omicron may be primed to overcome a broad range of coronavirus variants, early research suggests.  

A pair of studies showed that infection produced even better immune responses than a booster shot in vaccinated patients. Teams from Covid-19 vaccine maker BioNTech SE and the University of Washington posted the results on preprint server bioRxiv in recent weeks.

The findings offer a reassuring sign that the millions of vaccinated people who’ve caught Omicron probably won’t become seriously ill from another variant soon -- even though the research needs to be confirmed, especially by real-world evidence. 

“We should think about breakthrough infections as essentially equivalent to another dose of vaccine,” said John Wherry, a professor and director of the Institute for Immunology at the University of Pennsylvania who wasn’t involved in the research but reviewed the BioNTech study. That could mean that if someone had Covid recently, they could wait before getting another booster shot, according to Wherry. 

Alexandra Walls, a principal scientist at the University of Washington who authored one of the studies, cautioned that people shouldn’t seek out infections in response to the findings.

The data comes as Omicron continues to fuel outbreaks around the world, most notably in China, where residents of Shanghai have endured almost six weeks of lockdown. Waves of new variants are coming more quickly in part because Omicron is so transmissible, giving it ample opportunity to spread and mutate as countries drop restrictions, said Sam Fazeli, an analyst with Bloomberg Intelligence. Meanwhile, regulators are weighing whether Covid vaccines should be updated to target Omicron.

BioNTech’s team argued that the data indicate that offering people an Omicron-adapted booster shot may be more beneficial than multiple ones with the original vaccines.

The Washington research, conducted together with Vir Biotechnology Inc., looked at blood samples from people who had been infected, and then had two or three doses of vaccine, as well as those who’d caught the delta and Omicron variants after two or three doses; others still had been vaccinated and boosted but never caught Covid. A final group had only been infected with Omicron and never vaccinated.

One part of the study zeroed in on antibodies, the protective proteins tailored to recognise and neutralise invaders. It showed vaccinated people who’d caught Omicron had antibodies that outperformed the others. They were even capable of recognizing and attacking the very different delta variants. 

“That indicates that we are at the point where we may want to consider having a different vaccine to boost people,” said David Veesler, an assistant professor at the University of Washington, who led the research. The scientists were also able to identify antibodies in the nasal mucous of these patients, which could help them neutralise the virus as soon as it enters the body. 

Nasal sprays are poised to be the next weapon for fighting Covid

Both the Washington and BioNTech studies also looked at another piece of the immune system: B cells, a type of white blood cell that can kick in to produce a burst of fresh antibodies if they recognise a pathogen. People who’d had an Omicron breakthrough infection had a broader response from these useful cells than those who’d had a booster shot but no infection, the BioNTech team found. 

Crucially, the Washington team also found that the broad response was missing in unvaccinated people who had caught Omicron as their first exposure to the virus. This “would be a problem if a new variant that is significantly different emerged,” Veesler said. 

There’s no guarantee that future mutations will be as mild as Omicron, and the pandemic’s future is hard to predict since it depends not just on immunity in the population, but also on how much the virus mutates. 

Other researchers who reviewed the studies said the findings match up with the growing body of evidence for an immune boost from exposure to different virus variants via vaccination and infection. Scientists have also shown broad immune responses in people who caught delta after getting their shots. 

“Maybe this is an indication that an updated booster might be a good idea,” said Theodora Hatziioannou, a virologist at The Rockefeller University who helped lead a team that looked at breakthrough infections in a group of vaccinated people in New York City. 

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January 27,2025

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The Uniform Civil Code (UCC), a law that has faced long-standing criticism from the Opposition, will officially come into effect in Uttarakhand on January 27, making it the first state in independent India to put into effect such a law.

According to the state’s chief minister Pushkar Singh Dhami, the government has completed all preparations to implement the law, including getting approval of the rules for the implementation of the Act and training of officials concerned. The rationale given for the law is that it will bring about ‘uniformity in the society and ensure equal rights and responsibilities for all citizens.’

"UCC is just an offering made by our state in the great 'yagya' being performed by the Prime Minister to make the country a developed, organised, harmonious and self-reliant nation," PTI quoted Dhami as saying in a statement.

The BJP had made a promise to implement the Uniform Civil Code in Uttarakhand in the run-up to the 2022 assembly polls.These polls saw the party storming to power for a second consecutive term, something never done by any other party in the state since its creation in 2000.

According to CM Dhami, the historic mandate was because of the party's commitment to passing the UCC.

The Uniform Civil Code journey in Uttarakhand

The Uttarakhand state cabinet cleared a proposal to form an expert panel on the Uniform Civil Code in March 2022 in the first cabinet meeting after winning the assembly elections. The panel, headed by retired Supreme Court Judge Ranjana Prakash Desai, was constituted on May 27, 2022 to prepare the draft of the UCC.

The Desai committee submitted a comprehensive draft in four volumes, prepared after one and a half years of dialogue with different sections of the state's population. It was sent to the state on February 2, 2024 and just a few days later, the Uttarakhand assembly passed the UCC bill. President Droupadi Murmu gave it her assent in March 2024, nearly two years after the initial proposal.

Another expert committee was at work after that, headed by former chief secretary Shatrughna Singh. It was formed to frame the rules and regulations for the implementation of the Act. The Sinha committee submitted its report to the state government late last year.

The state cabinet gave its approval recently and authorised the chief minister to decide a date for its implementation. Dhami decided the date to be January 27, 2025, a day after the country celebrated its 76th Republic Day.

What is in the Uttarakhand UCC?

The Uniform Civil Code Act of Uttarakhand will govern and regulate the laws relating to marriage and divorce, succession, live-in relationships and related matters.

It sets equal marriageable age for men and women, grounds of divorce and procedures across all religions, and bans polygamy and 'halala'.

Doon University Vice Chancellor Surekha Dangwal, who was part of the panel that drafted the UCC and was among those who framed the rules for its implementation, described to PTI the provisions aimed at bringing about gender parity in matters of marriage, divorce and succession, treating all children as legitimate including those born of void or voidable marriages, simplifying the process of preparing a will and regulating live-in relationships as the most outstanding in the UCC. She termed gender parity across all religions as the spirit of UCC.

According to Duggal, the UCC makes registration of all marriages and live-in relationships mandatory. She also said that the government has created facilities to help people register their marriages online so that they do not have to run around government offices for it.

"Another remarkable feature of the UCC is that it treats all children as legitimate. We have in fact totally done away with the term illegitimate in the context of children," she said. The UCC also makes a special provision for defence personnel called "privileged will" which can be made both in writing or by word of mouth.

Any soldier or air force personnel engaged in an expedition or actual warfare or a mariner at sea can make a privileged will for which rules have been kept flexible.

UCC criticism

Opposition leaders have criticized the UCC, arguing that it may lead to societal division along religious lines and might be impractical and overly ambitious.
The debate surrounding the UCC extends beyond Uttarakhand, as Article 44 of the Indian Constitution advocates for a uniform civil code across the country. Prime Minister Narendra Modi has referenced the Supreme Court's direction on the need for a common code, stressing that fulfilling the vision of the Constitution's framers remains a national goal.

Uttarakhand's implementation of the UCC is likely to set a precedent, with other states potentially following suit. The success of the law's implementation will depend on its ability to balance individual rights and social harmony.

As Uttarakhand stands at the forefront of this legal revolution, the coming weeks will offer a clearer picture of how the UCC will be received, both in the state and across India. The state's experience with the UCC will undoubtedly shape the future of personal law reform in the country.

What is the implementation process?

Shailesh Bagauli, secretary (home), stated that the government will issue two notifications: one for the implementation of the UCC and another for the rules and regulations, officially launching the UCC in the state.

Dhami had promised to implement the UCC if re-elected during the 2022 state polls. After becoming CM, he appointed a five-member committee led by Justice Ranjana Prakash Desai to draft the code, which received feedback from over 2.3 lakh people, representing nearly 10% of Uttarakhand's families.

The 740-page draft was presented to the chief minister on February 2, 2024, approved by the cabinet on February 4, tabled in the assembly on February 6, and passed the following day. Governor Lt Gen Gurmit Singh (retd) approved the bill on February 28 and President Droupadi Murmu subsequently signed it on March 11.

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News Network
January 18,2025

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Israel’s Unit 8200 is a secretive cyber warfare team that is said to be building the artificial intelligence (AI) systems that helped the regime commit the genocide against Palestinian people in the Gaza Strip. According to a report, Unit 8200 is building AI systems for global tech and AI companies.

Former Unit 8200 members who specialize in AI, machine learning and big data are working for Meta, Google, Apple, Amazon, Microsoft, Open AI and Nvidia, which is an AI company determined to be the biggest in the world, the ¡Do Not Panic! website reported on Friday.

Former Unit 8200 spies specializing in AI are based worldwide, from San Francisco to New York, Spain to Switzerland, and London to Jerusalem al-Quds.

The report also said that AI leaders from Unit 8200 are now working for AI start-ups or heralded by corporate media as the next generation of AI.

The report revealed that most of these AI people have expressed support for Israel’s genocidal war against the people in Gaza. It was also exposed that not a single person from these people ever voiced opposition to Israel’s mass murder in Gaza.

Advocacy groups have also said AI and machine learning is central to the architecture of occupation and apartheid established before the genocidal Gaza campaign, from the use of facial recognition technology, and AI-directed guns at checkpoints, to spy apps known as ‘Blue Wolf’ and ‘Red Wolf’.

According to another report published in November last year, Israel has been employing an AI firing system jointly manufactured by an Indian arms company during its genocide in Gaza.

Citing documents and news reports, the Middle East Eye (MEE) news portal reported on November 20 that the occupation forces have been using the Arbel system since the beginning of the Israeli regime’s bloody war on Gaza.

Arbel was unveiled at a defense expo in Gandhinagar in the Indian state of Gujarat in October 2022 as a co-venture between Israeli Weapons Industries (IWI) company and India’s Adani Defense & Aerospace.

At the time, several Indian media described it as “India’s first AI-based firing system.”

In April 2024, IWI introduced Aber as a new “computerized small arms system” designed to increase combat lethality.

India, which is the largest purchaser of Israeli weapons, has in recent years become a major co-producer of Israeli weapons.

Israel unleashed its bloody Gaza onslaught on October 7, 2023, after the Hamas resistance group carried out its historic operation against the usurping entity in retaliation for the regime’s intensified atrocities against the Palestinian people.

The Tel Aviv regime has so far killed at least 46,788 Palestinians, mostly women and children, and injured 110,453 others, according to the Gaza Health Ministry.

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coastaldigest.com news network
January 16,2025

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Mangaluru, Jan 16: In an unimaginable twist of fate, the vibrant life of 19-year-old K Ahmed Shaheem was abruptly cut short on the evening of January 15, as he collapsed and passed away while enjoying a game of badminton with friends at Falnir, Mangaluru.

Shaheem, the beloved son of Shareef, originally from Addoor and currently residing at Ivory Tower, Attavar, Mangaluru, was in the prime of his youth. 

A student pursuing his graduation at a local private college, Shaheem had a bright future ahead, filled with dreams and ambitions. His sudden death has left family, friends, and the entire community in shock and grief.

Witnesses recount the heart-wrenching moment when Shaheem, in the middle of an energetic game, suddenly fell to the ground. His friends, devastated by the sight, rushed him to the hospital in the hope of saving his life. But tragically, doctors confirmed that he had passed away by the time he arrived.

Shaheem was not only a student, but also a passionate individual deeply involved in various social organizations, where he touched many lives with his kindness and commitment. His sudden departure has left a void that can never be filled, and his memory will remain forever etched in the hearts of all who knew him.

As his family mourns the loss of their precious son, the community stands in solidarity, deeply moved by the untimely loss of a young life that had so much promise.

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