India will have 'approved' vaccine by 2021 Q1: Bernstein Research

News Network
August 28, 2020

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New York, Aug 28: India is on course to have an "approved" vaccine within the first quarter of the calendar year 2021 and Pune based Serum Institute of India (SII), the world's largest vaccine manufacturer by volume, is well placed to deliver the first vaccine, according to a report out Thursday from Bernstein Research, a top Wall Street research and brokerage firm.

"Globally, there are four candidates that are close to approval by the end of the CY2020 or early 2021. Through partnerships India has access to two of those - AZ/Oxford's viral vector vaccine and Novavax's protein subunit vaccine with AZ/Oxford's vaccine ahead by a quarter," says the Bernstein report, which news agency has reviewed.

"With their existing capabilities and capacities, SII is best positioned to commercialize one or both of the partnered vaccine candidates depending on approval timing, capacities and pricing."

Data from Phase 1 and Phase trials look promising for both these candidates "in terms of safety and the vaccines' ability to elicit an immune response". The way things look now, the report indicates that both vaccine candidates "will require two doses to be administered 21/28 days apart".

The report strikes an upbeat tone on India's "global capacity equation" and does not foresee "manufacturing scale-up challenges".

Serum Institute of India, the report says, could supply 600 million doses in 2021 and 1 billion doses in 2022, out of which 400 to 500 million "should be available in India in 2021" in the context of the company's commitments to Gavi The Vaccine Alliance and lower and middle-income markets.

The report estimates that vaccine volumes will be split 55:45 between the government and the private market.

"We believe the government channel will have first access to the capacities but also believe there will be a sizable private market. In terms of funding, manpower and delivery infrastructure the Government will struggle to shoulder the burden on its own and we expect the private market to step in and supplement."

SII has announced that Gavi will procure vaccines at $3 per dose. The Bernstein report uses that as a benchmark to estimate procurement price to be around $3 a dose for the government and end consumer price of about $6 per dose.

Apart from SII, the report lists at least three other Indian pharma companies - Zydus, Bharat Biotech and Biological E - which are working on their own vaccine candidates and are currently in Phase 1 and 2.

Between SII, Bharat Biotech, Biological E, and some smaller players, India produces around 2.3 billion doses of various vaccines every year.

SII alone is the globally largest manufacturer of vaccines with 1.5 billion doses capacity. Every two out of three children globally get a shot manufactured by SII.

In early August, SII entered into a partnership with Gavi, The Vaccine Alliance and the Bill and Melinda Gates Foundation, to accelerate the manufacture and delivery of up to 100 million doses of COVID-19 vaccines for India and low- and middle-income countries (LMICs).

The collaboration pumps upfront capital to SII to help them increase manufacturing capacity now so that, once a vaccine, or vaccines, gains regulatory approval and WHO prequalification, doses can be produced at scale for distribution to India and lower and middle-income nations as quickly as the first half of 2021.

The overall vaccine market in India is estimated at "$6 billion spread over FY 21-22", according to Bernstein.

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News Network
September 13,2024

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NRI professionals hailing from the coastal and Malnad regions of Karnataka, now based in Singapore, Indonesia, Malaysia, Hong Kong, and Australia, have been urging the Indian government and airlines to introduce a direct flight between Mangalore International Airport (MIA) and Singapore’s Changi Airport.

These professionals argue that Singapore’s strategic location as a hub connecting India with East Asia makes this flight essential. They highlight that this route would serve over 12 million people from the coastal and hill regions of southern India, fostering stronger ties with East Asian economies.

The group, consisting of individuals from Dakshina Kannada, Uttara Kannada, Udupi, Chikkamagaluru, Kodagu, Shivamogga, and Hassan, is spearheaded by Rajesh H Acharya, director of HQ Connections Pte Ltd, Singapore, and coordinator of the Singapore Tuluver community. Acharya emphasized the significance of the Indian government’s Act East policy, which aims to strengthen relationships between India and ASEAN, East Asia, and the Asia-Pacific region.

“This flight will open new doors for cultural, trade, tourism, and technological exchanges between these regions,” Acharya said.

The Mangalore Chapter of IndUS Entrepreneurs (TiE) has also proposed positioning the region as the 'Silicon Beach of India.' A direct flight would provide greater opportunities for entrepreneurs and investors from both Singapore and Mangaluru, boosting business exchanges.

Moreover, Singapore’s Changi Airport could see increased tourism from the Karnataka coast, while Coastal Karnataka would benefit from a surge in visitors from ASEAN countries, the Far East, Australia, New Zealand, and the US West Coast.

While a similar attempt in 2017 did not succeed, Acharya and his team are hopeful that this time their appeal will be taken seriously, tapping into the immense growth potential of the eastern half of the globe.

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News Network
September 20,2024

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New Delhi: The Supreme Court today sought a report from the Karnataka High Court over controversial remarks made by Justice Vedavyasachar Srishananda during a recent court hearing.

Justice Srishananda, while addressing a landlord-tenant dispute, referred to a Muslim-majority area in Bengaluru as "Pakistan" and made a misogynistic comment involving a woman lawyer. 

A five-judge bench led by Chief Justice of India DY Chandrachud, along with Justices S Khanna, B R Gavai, S Kant, and H Roy, expressed the need for establishing clear guidelines for constitutional court judges regarding their remarks in court. 

The Supreme Court bench said that when social media plays an active role in monitoring and amplifying courtroom proceedings, there is an urgency to ensure judicial commentary aligns with the decorum expected from courts of law.

"Our attention has been drawn to some comments made by Karnataka High Court judge Justice V Srishananda during the conduct of judicial proceedings. We have asked the AG and SG to assist us. We ask the registrar general of the High Court to submit a report to this court after seeking administrative directions from the Chief Justice of Karnataka High Court. This exercise may be carried out in 2 weeks," the top court directed.

Videos of Justice Srishanananda have gone viral on social media.

In one video, he refers to a Muslim-dominated locality in Bengaluru as "Pakistan" and on another video he was seen making objectionable comments against a woman lawyer. In the second incident, Justice Srishanananda can be heard telling the woman lawyer that she seemed to know a lot about the "opposition party", so much so that she might be able to reveal the colour of their undergarments.

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News Network
September 12,2024

New Delhi, Sep 12: Madrasas are "unsuitable" places for children to receive "proper education" and the education imparted there is "not comprehensive" and is against the provisions of the Right to Education Act, the National Commission for Protection of Child Rights (NCPCR) has told the Supreme Court.

The child rights body told the top court that children, who are not in formal schooling system, are deprived of their fundamental right to elementary education, including entitlements such as midday meal, uniform etc.

The NCPCR said madrassas merely teaching from a few NCERT books in the curriculum is a "mere guise" in the name of imparting education and does not ensure that the children are receiving formal and quality education.

"A madrassa is not only a unsuitable/unfit place to receive 'proper' education but also in absence of entitlements as provided under Sections 19, 21,22, 23, 24, 25, and 29 of the RTE Act," it said.

"Further, madrasas do not only render an unsatisfactory and insufficient model for education but also have an arbitrary mode of working which is wholly in absence of a standardised curriculum and functioning," the NCPCR said in its written submissions filed before the top court.

The child rights body stated that due to the absence of provisions of the RTE Act, 2009, the madrassas are also deprived of entitlement as in Section 21 of the Act of 2009.

"A madrassa works in an arbitrary manner and runs in an overall violation of the Constitutional mandate, RTE Act and the Juvenile Justice Act, 2015. It cannot be overlooked that a child getting education in such an Institution will be devoid of basic knowledge of school curriculum which is provided in a school.

"A school is defined under Section 2(n) of the RTE Act, 2009, which means any recognised school imparting elementary education. A madrassa being out of this definition has no right to compel children or their families to receive madrassa education," the NCPCR said.

It said most of the madrassas fail to provide a holistic environment to students, including planning social events, or extracurricular activities for 'experiential learning.

In a breather to about 17 lakh madrassa students, the apex court on April 5 had stayed an order of the Allahabad High Court that scrapped the Uttar Pradesh Board of Madarsa Education Act, 2004 calling it "unconstitutional" and violative of the principle of secularism.

Observing that the issues raised in the petitions merit closer reflection, a three-judge bench headed by Chief Justice D Y Chandrachud had issued notices to the Centre, the Uttar Pradesh government and others on the pleas against the high court order.

The top court said had the high court "prima facie" misconstrued the provisions of the Act, which does not provide for any religious instruction.

The high court had on March 22 declared the Uttar Pradesh Board of Madarsa Education Act, 2004, "unconstitutional" and violative of the principle of secularism, and asked the state government to accommodate students in the formal schooling system.

The high court had declared the law ultra vires on a writ petition filed by advocate Anshuman Singh Rathore.

It had said the state has "no power to create a board for religious education or to establish a board for school education only for a particular religion and philosophy associated with it."

"We hold that the Madarsa Act, 2004, is violative of the principle of secularism, which is a part of the basic structure of the Constitution," the high court had said.

The petitioner had challenged the constitutionality of the UP Madarsa Board as well as objected to the management of madrassas by the Minority Welfare Department instead of the education department.

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