Enhanced Delta+ variant of Covid-19 seen in 6 states including Karnataka

News Network
June 15, 2021

Bengaluru, June 15: A dangerous new Covid-19 variant that is potentially resistant to certain drugs has been found in Karnataka and other states with experts stressing the need for close monitoring of the situation.

Research suggests that the new variant, which is officially designated B.1.617.2.1 (or alternatively as AY.1) was first spotted in India on April 5.

Since then and up to May 15, seven additional sequences were identified in five other states, besides one from Karnataka.

According to experts, the increased mobility of people in March and April prior to the lockdown imposed on April 27, could have triggered the mutation, especially as it is a derivative of the B.1.617.2 “Delta” variant which experts already blame for driving the second wave.

Speaking as an independent authority, associate professor Amit Singh, head, Centre for Infectious Disease Research, Indian Institute of Science (IISc), said the larger the scale of the infections, the more opportunity for a virus to add a “gain of function” mutation.
 
“This is a mutation which gives a typical virus increased transmissibility, virulence, immunogenicity,” he said.

Well known virologist Dr V Ravi, who is also the chairman of the state’s Genomic Surveillance Committee, said that there was precedent to show that previous variants of the novel coronaviruses obtained same mutations independently across various geographic regions. 

Dr Vishal Rao, also a member of the Committee, said that the state does not know how many of the sequences are coming from airline passengers of the ongoing “air bubble” international flights and how many are coming from hospitals.

“There is no data. We also need to get clinical correlation by monitoring ICUs and hospitals to find out what the genomic pattern and behavior is. We are not keeping our ears to the ground,” he said.

What is known is that the sequences have been found in states which reported some of the highest incidences of Covid-19 cases in the second wave: Karnataka, Maharashtra, Andhra Pradesh, Gujarat and Tamil Nadu. Odisha also found one sequence.

The largest number of sequences found so far have been in Tamil Nadu (three sequences found out of 562 genome samples). In Karnataka, the sole sequence was found among 1,115 samples.

At the same time, the number of Delta+ sequences being found in India are increasing. Up to June 11, six sequences had been made public. This rose to seven on June 13 and finally to eight on Monday.

Some 158 sequences of the Delta+ have been found across 11 countries to date: Nepal, Portugal, Poland, Switzerland, Japan, Russia, Turkey, the UK, the US and Canada. The first global cases were found on March 29.

What makes Delta+ a concern is that it has picked up a key new mutation in the S protein according to scientists at Delhi’s CSIR-Institute of Genomics and Integrative Biology. This allows it to evade an immune response. The new variant is also potentially resistant to monoclonal antibody cocktail, which has been hailed as a cure.

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News Network
January 8,2025

Mangaluru: Air India Express (AIE) has postponed its much-anticipated direct flight service between Mangaluru International Airport (MIA) and Singapore, citing low bookings. Passengers who had booked tickets for the inaugural flight scheduled for January 21 and subsequent dates have been notified of the cancellation through email.

In its email, AIE assured passengers of alternative travel arrangements, including connecting flight options between MIA and Singapore. However, the decision to delay the direct service has left travelers and travel agents disappointed.

An AIE official attributed the postponement to operational challenges but clarified that the airline has not abandoned plans for the route. “We are committed to starting the service, but there is no immediate confirmation on the new launch date,” the official stated. He further explained that sustaining a route requires consistent demand, and seasonal travel alone is insufficient to justify operations.

Another AIE representative admitted that the number of bookings for the inaugural flight was below expectations but declined to disclose specific figures.

Rajesh H Acharya, director of HQ Connections Pte Ltd in Singapore and coordinator of the Singapore Tuluver community, expressed his disappointment. Acharya, who has been advocating for a direct flight between Mangaluru and Singapore since 2017, said, “After years of effort, we finally convinced the airline to start this service, but it has now been deferred.”

Taking to X (formerly Twitter), Acharya posted: "Did not expect such behavior from @AirIndiaX, now owned by @TataCompanies & @SIAirlines. If there are issues, travelers deserve to be informed well in advance. This decision needs investigation at the highest level."

The delay has raised questions among the travel community, with many hoping the airline will address these concerns and provide a clear timeline for the launch of the Mangaluru-Singapore direct flight.

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News Network
January 6,2025

Two cases of Human Metapneumovirus (HMPV) were reported in Bengaluru on January 6 - a 3-month-old baby who has been discharged and an 8-month-old who is recovering at a hospital in the Karnataka capital. This marks the first reported cases of HMPV in India.

The infected infants and their families have no recent travel history, ruling out exposure from other regions or countries, the health department said.

HMPV is a respiratory virus that often causes mild symptoms resembling a cold but can lead to other complications, particularly in infants, the elderly, and those with weakened immune systems. The virus can occasionally trigger pneumonia or exacerbate chronic respiratory conditions. Cases typically rise during the winter and early spring.

The Centre announced on Sunday that it is monitoring HMPV and other respiratory viruses, especially following recent reports of increased respiratory illnesses in China. A Joint Monitoring Group (JMG) convened on January 4 to evaluate the situation, with representatives from the World Health Organisation (WHO), National Centre for Disease Control (NCDC), Indian Council of Medical Research (ICMR), and other health organisations participating.

Respiratory illnesses in China align with seasonal variations caused by viruses such as influenza, RSV, and HMPV. Current surveillance data from India does not indicate any unusual surge in respiratory infections, according to the Ministry of Health and Family Welfare.

As a precaution, the Centre has increased laboratory capacity for HMPV testing. The ICMR will monitor HMPV trends throughout the year, alongside other respiratory illnesses such as influenza-like illness (ILI) and severe acute respiratory infections (SARI). A robust network of surveillance systems, including those operated by ICMR and the Integrated Disease Surveillance Programme (IDSP), continues to track respiratory infections across the country.

Hospitals have been advised to strengthen isolation protocols for suspected cases, ensure the availability of essential medicines, and promptly report ILI and SARI cases through the Integrated Health Information Platform (IHIP).

Precautions to Take:

To reduce the risk of HMPV infection, individuals are advised to:

  • Wash hands frequently with soap and water for at least 20 seconds.
  • Avoid close contact with people who have respiratory symptoms.
  • Wear masks in crowded or high-risk areas, especially during seasonal outbreaks.
  • Maintain good indoor ventilation by keeping windows open when possible.
  • Disinfect commonly touched surfaces regularly, such as doorknobs, toys, and tables.
  • Monitor infants, the elderly, and people with chronic illnesses for symptoms like persistent cough or breathing difficulties.
  • Seek prompt medical attention if respiratory symptoms worsen or persist. 

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News Network
January 3,2025

Karnataka's Urban Development Minister, BS Suresha (Byrathi), has initiated a detailed investigation into ₹5,527 crore worth of projects executed under Prime Minister Narendra Modi’s flagship Smart Cities Mission in six cities of the state.

The minister expressed dissatisfaction with the quality of work in Belagavi, Davangere, Hubballi-Dharwad, Mangaluru, Shivamogga, and Tumakuru. To ensure accountability, Suresha announced the formation of a committee comprising experts from universities and the Indian Institute of Science. The committee will assess the projects and submit its findings within three months.

Bengaluru, however, is excluded from the probe as it falls under the jurisdiction of Deputy Chief Minister DK Shivakumar.

Launched in 2015, the Smart Cities Mission aims to enhance urban infrastructure across 100 cities in India, funded jointly by the central and state governments. Karnataka has spent ₹6,405 crore under this mission, including ₹877.72 crore in Bengaluru.

"Most of the funds have been allocated to roads, drainage, and park maintenance," Suresha lamented in a statement. "The focus should have been on creating permanent infrastructure such as smart schools, hospitals, libraries, and bus stands."

Suresha pointed out that, on average, each Smart City in Karnataka received ₹990 crore, with spending patterns revealing 36% on roads, 8% on energy, 2% on education, 2% on healthcare, and 5% on sports. He criticized this distribution, emphasizing that projects under the mission should have developed long-lasting government assets instead of temporary solutions like roads and drains.

With the mission slated to conclude in March 2025, Suresha urged the remaining funds to be directed towards constructing world-class smart schools. "This will enable children from economically weaker sections to access quality education," he said.

The minister also revealed that he had received multiple complaints from elected representatives about substandard work, particularly in Belagavi, Hubballi-Dharwad, and Shivamogga. The probe, he assured, will prioritize transparency and accountability.

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